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Multiplex analysis of the tumor microenvironmentWebinarIn this animated video, learn how spatial biology is used to interrogate the tumor microenvironment. You'll learn about key immune cell populations that are found within the tumor microenvironment and how spatial biology techniques can be used for biomarker identification and patient stratification.
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Overcoming Challenges in CRISPR ApplicationsArticleIdeas for troubleshooting CRISPR experiments include addressing off-target effects, increasing delivery efficiency, avoiding immune responses, and improving enzyme stability.
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Infographic: Multiplex immunofluorescence techniques explainedInfographicMultiplex immunohistochemistry-immunofluorescence (mIHC/mIF) techniques enable the simultaneous detection of multiple proteins of interest in a single sample. This provides numerous benefits in the examination of different tissues, such as a tumor biopsy. Learn about the benefits of mIHC/mIF experimental approaches and key spatial biology techniques. such as tyramide signal amplification (TSA) and cyclic immunofluorescence.
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Podcast: Mitochondria, the immune system and cancer- discovering new insights with spatial technologiesPodcastIn this podcast, produced in collaboration with BioTechniques, we delve into the relationship between mitochondria, inflammation and cancer, discussing the new techniques that are bearing fruit in this field, such as spatial analysis. Guest speaker: Dr. Phillip West, formerly at Texas A&M Medicine and now at The Jackson Laboratory.
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Advantages of Recombinant Monoclonal Antibodies over Hybridoma-Derived AntibodiesArticleRecombinant monoclonal antibodies have emerged as a superior alternative to hybridoma-derived monoclonal antibodies, offering numerous advantages in antibody production and application. This article explores the benefits of recombinant techniques over traditional hybridoma methods, focusing on considerations such as reproducibility, scalability, storage, and the increasing role of recombinant antibodies in diagnostics and therapeutics.
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