Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]
Catalog #
Granzyme B
Human
ICC
,IHC
,IHC-IF
,mIF
,WB
COMET™
,PhenoImager™ HT
Rabbit
Recombinant Monoclonal
BLR022E
Whole IgG
Residues 19-247 (mature protein)
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
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Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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The monoclonal antibody was purified from cell culture supernatant.
Immunogen was a recombinant protein representing human Granzyme B (residues 19-247, NP_004122.2).
The monoclonal antibody was purified from cell culture supernatant.
Immunogen was a recombinant protein representing human Granzyme B (residues 19-247, NP_004122.2).
USA
Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
Alternate Names
C11; cathepsin G-like 1; CCPI; CGL1; CGL-1; CSPB; CSP-B; CTLA1; CTLA-1; CTSGL1; cytotoxic serine protease B; cytotoxic T-lymphocyte proteinase 2; fragmentin 2; Fragmentin-2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Granzyme-2; HLP; human lymphocyte protein; Lymphocyte protease; SECT; T-cell serine protease 1-3E
Applications