/ Antibodies & Antigens / Primary Antibodies / Mouse anti-CD45 Monoclonal Antibody [BLGM039]
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Mouse anti-CD45 Monoclonal Antibody [BLGM039]

bethyl
Bethyl Laboratories Catalog #
Target:
CD45
Reactivity:
Human
Applications:
IHC
Host:
Mouse
Clonality:
Monoclonal
Clone:
BLGM039
Format:
Whole IgG
Isotype:
IgG1
Conjugate:
Unconjugated
Purity:
Purified
100 µl

20 µl

$136.00 $516.00
Qty:
Bulk Request

Product Details

Specifications

Reactivity
Human
Antigen Species
Human
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline with 1% BSA and <0.1% Sodium Azide
Request Formulation Change
Country of Origin
USA

Additional Product Information

CD45 is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. CD45 acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45 recruits and dephosphorylates SKAP1 and FYN [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P08575].

5788
PTPRC
protein tyrosine phosphatase, receptor type C
P08575
Receptor-type tyrosine-protein phosphatase C

Alternate Names

B220;CD antigen CD45;CD45;CD45 antigen;CD45R;GP180;LCA;L-CA;Leukocyte common antigen;LY5;protein tyrosine phosphatase, receptor type, c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen