Mouse anti-IGF1R Monoclonal Antibody [BC10]
Product Details
Specifications
Request Formulation Change Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide, BSA-Free
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Additional Product Information
IGF1R is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1) and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. IGF1R is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [taken from NCBI Entrez Gene (Gene ID: 3480)].
Alternate Names
CD antigen CD221; CD221; IGF-I receptor; IGFIR; IGFR; insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; JTK13; soluble IGF1R variant 1; soluble IGF1R variant 2