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Mouse anti-p53 Monoclonal Antibody [BLGM140]

bethyl
Bethyl Laboratories Catalog #
Target:
p53
Reactivity:
Human
Applications:
IHC
Host:
Mouse
Clonality:
Monoclonal
Clone:
BLGM140
Format:
Whole IgG
Isotype:
IgG2b
Conjugate Type:
Unconjugated
Purity:
Purified
100 µl

20 µl

$136.00 $516.00
Qty:
Bulk Request

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline with 1% BSA and <0.1% Sodium Azide
Request Formulation Change
Country of Origin
USA

Additional Product Information

p53 is a tumor suppressor protein that is mutated or inactivated in over 50% of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis.

7157
TP53
tumor protein p53
P04637
Cellular tumor antigen p53

Alternate Names

antigen NY-CO-13;BCC7;cellular tumor antigen p53;LFS1;mutant tumor protein 53;P53;p53 tumor suppressor;phosphoprotein p53;transformation-related protein 53;TRP53;tumor protein 53;Tumor suppressor p53;tumor supressor p53