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Mouse anti-TS Monoclonal Antibody [BLGM171]

bethyl
Bethyl Laboratories Catalog #
Target:
TS
Reactivity:
Human
Applications:
IHC
Host:
Mouse
Clonality:
Monoclonal
Clone:
BLGM171
Format:
Whole IgG
Isotype:
IgG1
Conjugate:
Unconjugated
Purity:
Purified
100 µl

20 µl

$136.00 $516.00
Qty:
Bulk Request

Product Details

Specifications

Reactivity
Human
Antigen Species
Human
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Tris-buffered Saline with 1% BSA and <0.1% Sodium Azide
Request Formulation Change
Country of Origin
USA

Additional Product Information

Thymidylate synthetase (TS) catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. TS is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs [taken from NCBI Entrez Gene (Gene ID: 7298)].

7298
TYMS
thymidylate synthetase
P04818
Thymidylate synthase

Alternate Names

HST422;thymidylate synthase;TMS;TS;TSase