Rabbit anti-4EBP1 Antibody Affinity Purified
Catalog #
4EBP1
Human
IHC
,WB
Rabbit
Polyclonal
Whole IgG
Between 68 and C-terminus
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Rat
Rat
Human
2 - 8 °C
1 year from date of receipt
USA
Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) binds directly to eIF4E to inhibit complex assembly for translation initiation. 4EBP1 is part of a family of translation repressor proteins. 4EBP1 is directly phosphorylated by the mTORC1 complex during growth factor stimulation of cells. Phosphorylation of 4EBP1 causes its release from eIF4E to allow translation to proceed.
Eukaryotic translation initiation factor 4E-binding protein 1
Alternate Names
4EBP1; 4E-BP1; BP-1; eIF4E-binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; phosphorylated heat- and acid-stable protein regulated by insulin 1
Applications