Rabbit anti-Phospho RPA32 (S33) Recombinant Monoclonal Antibody [BLR364N]
Product Details
Specifications
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Immunogen was a phosphorylated peptide representing a region of human Replication Protein A2, 32 kDa (aka RPA32) surrounding Serine 33 according to the numbering given in entry NP_002937.1 (Gene ID 6118).
Additional Product Information
Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA2, the 32kDa subunit, is phosphorylated by the cdc2 family of kinases when cells enter S-phase and in response to DNA damage by ATM, ATR, and DNA-PK.
Alternate Names
REPA2; replication factor A protein 2; replication protein A 32 kDa subunit; replication protein A 34 kDa subunit; RF-A protein 2; RP-A p32; RP-A p34; RPA32