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Validate Your AntibodiesPosterOvercome poor results from poorly characterized antibodies with this poster offering quick tips and considerations when it comes to antibody validation.
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Tumor Infiltrating Lymphocytes (TILs)PosterLearn about the various roles and interactions of key tumor and immune cell types within the tumor microenvironment.
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Apoptosis PathwayJanuary 11, 2023PosterApoptosis is one mechanism of cell death, and can be triggered either by an extracellular, extrinsic pathway or a mitochondrial, intrinsic pathway. Resistance or over-sensitivity to apoptosis is a cause of a number of disease states and makes an understanding of this pathway critical for the advancement of human health.
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MAPK PathwayJanuary 11, 2023PosterThe MAPK pathway translates extracellular stimuli, such as the presence of growth factors or cytokines, into significant changes to transcription, cellular proliferation, and inflammation. Though there are distinct paths within the MAPK pathway, the downstream effects are largely similar and their role in proliferation and differentiation makes it particularly critical for cancer research.
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p53 PathwayJanuary 11, 2023Posterp53, the prototypical tumor suppressor, is a critical intracellular translator of extracellular signals such as UV- or gamma-radiation, nutrient depravation, or genotoxic drugs. In coordination with the regulatory effects of other proteins such as HdmX, p53 activation regulates a huge number of genes and results in cell cycle arrest, inhibition of angiogenesis, and a number of other effects. Mutated in over half of human cancers, understanding this protein and its pathways will have a significant impact on human health.