Rabbit anti-BAP1 Recombinant Monoclonal Antibody [BLR372N]
Product Details
Specifications
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Immunogen was a peptide representing a region between residue 475 and 525 of human Ubiquitin carboxyl-terminal hydrolase BAP1 using the numbering given in entry NP_004647.1 (Gene ID 8314).
Additional Product Information
BRCA1-associated protein 1 (BAP1) functions as a C-terminal ubiquitin hydrolase and may be involved in the transduction of signals in the BRCA1 pathway. BAP1 is also implicated to be a tumor suppressor as defects in BAP1 are found in non-small cell lung cancer cell lines.
Alternate Names
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase); BRCA1-associated protein 1; cerebral protein 6; cerebral protein-13; HUCEP-13; hucep-6; ubiquitin carboxyl-terminal hydrolase BAP1; UCHL2
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (A120-101P).
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (A120-113P) with 5% Normal Pig Serum (S100-020) added to the blocking buffer.